Advanced EGFR+ NSCLC

Advanced EGFR+ NSCLC

  • EGFR stands for epidermal growth factor receptor. EGFR is a protein found on the surface of normal cells and cancer cells.

    • In EGFR+ NSCLC, a change in the EGFR gene causes abnormal growth. This can make it grow too much and cause cancer.

      • Different types of EGFR mutations can occur.

        • The most common mutations are called EGFR Exon 19 deletion or Exon 21 L858R.

          • There are mutations also called EGFR exon 20 insertion.

            • Less common mutations may include:

              • EGFR S768I

              • EGFR L861Q

              • EGFR G719X

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