Common side effects

Some people may experience common side effects that may include:

Digestive system issues (e.g., diarrhea, vomiting, nausea)

Skin concerns (e.g., rash, dry skin)

Mouth pain and sores

Nail changes or discoloration

Tiredness

Muscle pain

Important considerations

Some people may experience unusual but serious side effects that may include:

Infusion reactions (e.g., trouble breathing, flushing)

Tear (called perforation) in your intestine

Heart problems

Kidney problems

Inflammation of the lungs

Fetal harm

This site is published by Johnson & Johnson and its affiliates which is solely responsible for its contents. The material on this site is intended only as informational or as an educational aid and it is not intended to be taken as medical advice. The ultimate responsibility for patient care resides with a healthcare professional.

This information is intended for the use of patients and care partners in the United States only. Laws, regulatory requirements, and medical practices for pharmaceutical products vary from country to country. The Prescribing Information included here may not be appropriate for use outside the United States. Third party trademarks used herein are trademarks of their respective owners. Last updated April 2025.

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